19 Supplement 1 : 25—33 | Biological rhythms, sleep, and hypnosis |
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"Autoimmunity: A new clue to sleepiness" | The VLPO neurons inhibit and are inhibited by the TMN histamine neurons and REM-off monoamine neurons |
25 5 Suppl : S5—13.
6United States Food and Drug Administration | Miyagawa T, Honda M, Kawashima M, Shimada M, Tanaka S, Honda Y, Tokunaga K; Honda; Kawashima; Shimada; Tanaka; Honda; Tokunaga 30 April 2009 |
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Exploring the Mystery of REM Sleep | Consequently, the norepinephrine and serotonin REM-off cells, which are excited by orexin neurons during wakefulness, start to wane in activity, which gradually releases the cholinergic REM-on cells from their inhibitory effect |
A search for small-molecule agonists at orexin receptors is underway and could lead to a treatment for narcolepsy.
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